PROST: A quantitative pattern recognition framework for spatial transcriptomics

PROST is a flexible framework to quantify gene spatial expression patterns and detect spatial tissue domains using spatially resolved transcriptomics with various resolutions. PROST consists of two independent workflows: PROST Index (PI) and PROST Neural Network (PNN).


Using PROST you can do:

  • Quantitative identification of spatial patterns of gene expression changes by the proposed PROST Index (PI).

  • Unsupervised identification of spatial tissue domains using a PROST Neural Network (PNN).